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Incidental diagnosis of pediatric chronic myeloid leukemia in the setting of acute appendicitis: A case report and review of management strategies
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  • Zhidong Wang,
  • Jake Gigliotti,
  • Christine Gough ,
  • Claire Gallion,
  • Afshin Ameri
Zhidong Wang
Augusta University Medical College of Georgia

Corresponding Author:zhiwang@augusta.com

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Jake Gigliotti
Augusta University Medical College of Georgia
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Christine Gough
Augusta University Medical College of Georgia
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Claire Gallion
Augusta University Medical College of Georgia
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Afshin Ameri
Augusta University Medical College of Georgia
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Abstract

Chronic myeloid leukemia (CML) is rare in children, accounting for 2-3% of pediatric leukemias. We present a case of a 10-year-old with acute appendicitis leading to the incidental discovery of CML. Due to concerns about leukostasis and tumor lysis syndrome, immediate surgical intervention was deferred in favor of medical management with antibiotics and hydroxyurea, followed by appendectomy once the leukocytosis improved. This case highlights the successful use of medical management as a bridge to surgery, providing novel insights into management of co-occurring appendicitis and CML in pediatric patients.
08 Aug 2024Submission Checks Completed
08 Aug 2024Assigned to Editor
08 Aug 2024Submitted to Pediatric Blood & Cancer
09 Aug 2024Review(s) Completed, Editorial Evaluation Pending
12 Aug 2024Editorial Decision: Revise Minor
26 Aug 2024Assigned to Editor
26 Aug 2024Submission Checks Completed
26 Aug 20241st Revision Received
27 Aug 2024Review(s) Completed, Editorial Evaluation Pending
28 Aug 2024Editorial Decision: Accept