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Volumetric Magnetic Resonance Imaging Study Of The Anterior Cingulate Cortex And Caudate Nucleus In Obsessive-Compulsive Personality Disorder
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  • Tuba Yilmaz,
  • Murad Atmaca,
  • Muhammed Tabara,
  • Sevler Yildiz,
  • Hanefi Yildirim
Tuba Yilmaz
Elazıg Fethi Sekin City Hospital
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Murad Atmaca
Firat Universitesi Tip Fakultesi
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Muhammed Tabara
Firat University School of Medicine

Corresponding Author:fatihtabara@gmail.com

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Sevler Yildiz
Elazıg Fethi Sekin City Hospital
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Hanefi Yildirim
Firat University School of Medicine
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Abstract

The present study measured the anterior cingulate cortex (ACC) and caudate nucleus (CN) volumes of patients diagnosed with obsessive-compulsive personality disorder (OCPD) and compared them with healthy controls with an aim to investigate its neuroanatomy of. The Sociodemographic and Clinical Data Form, Beck Anxiety Scale (BAS), Beck Depression Scale (BDS), and Frost Multidimensional Perfectionism Scale (FMPS) were administered to 18 healthy controls and 16 patients diagnosed with OCPD. Volumetric measurements of the right/left ACC and CNs were performed for all the participants through brain magnetic resonance imaging. There was no significant difference between patients and controls by ACC and CN volumes. BAS, BDS, and FMPS scale scores in the patient group were statistically higher compared to the control group. Volumetric changes in the ACC and CN do not play a role in the pathophysiology of OCPD. Functional imaging techniques may be useful in explaining the likely role of these regions in the etiopathogenesis of the disease.
Submitted to European Journal of Neuroscience
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04 Jul 2024Review(s) Completed, Editorial Evaluation Pending