Role of Wnt5a in inflammatory diseases
- Kui Li,
- Xin-ning Guo,
- Jia-wei Li,
- Kaijin Wang,
- Xin-hua Yu,
- Bi-cui Liu
Xin-ning Guo
Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital
Author ProfileJia-wei Li
Bishan Hospital of Chongqing Medical University
Author ProfileKaijin Wang
Bishan Hospital of Chongqing Medical University
Author ProfileXin-hua Yu
Bishan Hospital of Chongqing Medical University
Author ProfileBi-cui Liu
Bishan Hospital of Chongqing Medical University
Corresponding Author:liuyuan2469@163.com
Author ProfileAbstract
Wnt5a plays an important role in the process of cell development and
maturation and is closely related to various diseases, such as malignant
tumors, metabolic disorders, fibrosis, growth and development. Recent
studies have shown that Wnt5a expression regulation and signal
transduction are closely related to inflammatory response. This paper
comprehensively reviews the latest research progress on the relationship
between Wnt5a and various inflammatory diseases, such as sepsis, asthma,
chronic obstructive pulmonary disease, tuberculosis, rheumatoid
arthritis, atherosclerosis, psoriasis vulgare, etc. The mechanism of
Wnt5a protein in the pathogenesis of these diseases was elucidated,
which provided a basis for the prevention and treatment of inflammatory
diseases with Wnt5a as a possible target in the future.Submission Checks Completed
Assigned to Editor
Reviewer(s) Assigned
22 Jun 2024Review(s) Completed, Editorial Evaluation Pending
14 Jul 2024Reviewer(s) Assigned
23 Aug 2024Editorial Decision: Revise Minor
02 Oct 20241st Revision Received
08 Oct 2024Submission Checks Completed
08 Oct 2024Assigned to Editor
08 Oct 2024Review(s) Completed, Editorial Evaluation Pending
08 Oct 2024Reviewer(s) Assigned
22 Nov 2024Editorial Decision: Accept