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Sociodemographic inequities in food allergy: Insights on food allergy from birth cohorts
  • Christopher Warren,
  • Tami Bartell R
Christopher Warren
Northwestern University Feinberg School of Medicine

Corresponding Author:christopher.warren@northwestern.edu

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Tami Bartell R
Northwestern University Feinberg School of Medicine
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Abstract

A large and growing corpus of epidemiologic studies suggests that the population-level burden of pediatric FA is not equitably distributed across major sociodemographic groups, including race, ethnicity, household income, parental educational attainment, sex). As is the case for more extensively studied allergic disease states such as asthma and atopic dermatitis) epidemiologic data suggest that FA may be more prevalent among certain populations experiencing lower socioeconomic status (SES), particularly those with specific racial and ethnic minority backgrounds living in highly urbanized regions. Emerging data also indicate that these patients may also experience more severe FA-related physical health, psychosocial and economic outcomes relating to chronic disease management. However, many studies that have identified sociodemographic inequities in FA burden are limited by cross-sectional designs that are subject to numerous biases, which can reduce the epidemiologic utility of the resulting estimates. Compared to cross-sectional study designs or cohorts that are recruited during childhood, birth cohorts can offer advantages relative to other study designs when investigators seek to understand causal relationships between exposures occurring during the prenatal or postnatal period and the atopic disease status of individuals later in life. Numerous birth cohorts have been established across recent decades, which include evaluation of food allergy-related outcomes, and a subset of these also have measured sociodemographic variables that, together, have the potential to shed light on the existence and possible etiology of sociodemographic inequities in food allergy. This manuscript attempts to survey the current state of this birth cohort literature and draw insights regarding what is currently known, and what further information can potentially be gleaned from thoughtful examination and further follow-up of ongoing birth cohorts across the globe.
Submitted to Pediatric Allergy and Immunology
16 Feb 2024Review(s) Completed, Editorial Evaluation Pending
18 Mar 20241st Revision Received
19 Mar 2024Assigned to Editor
19 Mar 2024Submission Checks Completed
19 Mar 2024Review(s) Completed, Editorial Evaluation Pending
21 Mar 2024Editorial Decision: Accept