EVALUATION OF MATERNAL AND NEONATAL OUTCOMES OF 523 PREGNANT WOMEN WITH
COVID-19 IN A SINGLE-CENTRE : A RETROSPECTIVE CROSS-SECTIONAL STUDY
Abstract
Objective: To evaluate the maternal, perinatal and neonatal outcomes for
pregnant women having tested positive for COVID-19 with the reverse
transcription polymerase chain reaction (RT-PCR) technique. Design:
Retrospective study. Setting: University‐affiliated hospital.
Population: Pregnant women with confirmed COVID-19 infection. Methods:
PCR tests were administered to the women presenting with clinical
complaints indicative of suspected COVID-19, or admitted to the hospital
for obstetric reasons. The present study used clinical records to
collect data such as general characteristics, clinical signs and
symptoms, laboratory findings and radiological imaging results of the
pregnant women, as well as the types of delivery and RT-PCR data of the
newborns from the women who gave birth. Main outcome measures: Data
related to the courses of pregnancy, maternal symptoms, types of
delivery, and neonatal outcomes. Results: 523 pregnant women tested
positive for COVID-19 with RT-PCR technique. Of these pregnant women,
411 had asymptomatic while 112 women showed at least one symptom. Of the
523 pregnant women in total, 384 maintained their pregnancies.
Eventually, 135 women gave birth. Twelve pregnant women (2.2%) in total
were treated in the intensive care unit, and three (0.6%) died with
COVID-19. All the newborns tested with the RT-PCR technique. All the
test results were negative. Conclusion: The existing data show that
pregnant women with COVID-19 infection may need to be admitted to
intensive care, and they may even be under a serious risk of maternal
morbidity which may result in maternal death. Funding: None