Given the economic challenges faced by countries in the South Asia following the COVID-19 pandemic and the Monkeypox (Mpox) outbreak, it becomes important to bring to the forefront the discussion regarding the impact of economic crises on healthcare systems of these nations and subsequently the influence on health planning and policy making. In order to facilitate a discussion on policy implications, we outline potential barriers, particular to health system of Pakistan and in general to the health infrastructure of South Asia, and present recommendations built on nine themes of community resilience in light of the current Monkeypox (Mpox) outbreak.