Rapid and timely virus detection by optical technologies: prospects for
future viruses’ prevalence
Abstract
The development of sensitive, fast, and more reliable diagnostic methods
to prevent and control the outbreak of life-threatening pandemic
infectious diseases, such as COVID-19, according to the WHO
recommendations, is always in priority and necessity. Optical diagnostic
methods, with their progress in technology, are central to most
applications and now, in the health field, are an alternative to
conventional methods because of their great sensitivity and capability
utilized for SARS-CoV-2 detection such as generally applied PCR
technology which is time-consuming, effortful, and has limited
availability in resource-limited situations. Herein, we reviewed various
optical methods engaged for virus detection such as fluorescence-based
techniques, Raman spectroscopy (RS), Plasmonic methods (e.g., SPR, LSPR,
SEF, and SERS), ATR-FTIR, super-resolution microscopy (SRM), and some
integrated platforms like waveguides and MIP-based biosensors for the
development of portable, sensitive, specific, and low-cost POC apparatus
for the rapid virus detection.