loading page

Research on evolution process of full-layer incision of skin tissue under different laser incidences
  • +2
  • Kehong Wang,
  • Yuxin Chen,
  • Jun Huang,
  • Yunfeng Rui,
  • Wentao Fan
Kehong Wang
Nanjing University of Science and Technology School of Science

Corresponding Author:wkh1602@126.com

Author Profile
Yuxin Chen
Nanjing University of Science and Technology School of Science
Author Profile
Jun Huang
Nanjing University of Science and Technology School of Science
Author Profile
Yunfeng Rui
Southeast University Zhongda Hospital Department of Orthopedics
Author Profile
Wentao Fan
Nanjing Medical University The Fourth School of Clinical Medicine
Author Profile

Abstract

Considering difficulties of achieving vertical incidence of beam in different positions of skin, it’s significant to study potential effects of incidence angles of laser on incisions. Surgical platform with a 1064nm continuous fiber laser was established. Incident angle was adopted and real-time temperature fluctuations in laser operating area could be monitored. The rats were treated with laser at day 0 and day 3 after incision modeling, and H&E, Masson, Sirius Red and Immuno-histochemical staining and enzyme-linked immunosorbent assay were adopted at day 3,7,14 to analyze the performance of healing. Laser with energy density of 67.54J/mm 2 can effectively accelerate wound healing in vivo, in which laser with incident angle around 60° can effectively avoid scar hyperplasia. Therefore, the use of low energy laser with small deflection angle has a good clinical application prospect in promoting wound healing.
23 Jul 2023Submitted to Journal of Biophotonics
25 Jul 2023Submission Checks Completed
25 Jul 2023Assigned to Editor
25 Jul 2023Review(s) Completed, Editorial Evaluation Pending
25 Jul 2023Reviewer(s) Assigned
14 Aug 2023Editorial Decision: Revise Major
21 Aug 20231st Revision Received
21 Aug 2023Submission Checks Completed
21 Aug 2023Assigned to Editor
21 Aug 2023Review(s) Completed, Editorial Evaluation Pending
21 Aug 2023Reviewer(s) Assigned
07 Sep 2023Editorial Decision: Accept