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Changes in medication initiation and selection patterns for gestational diabetes management
  • +5
  • Amelie Pham,
  • Rena Shi,
  • Andrew D. Wiese,
  • Andrew J. Spieker,
  • Sharon E. Phillips,
  • Margaret A. Adgent,
  • Carlos G. Grijalva,
  • Sarah S. Osmundson
Amelie Pham
Vanderbilt University Medical Center

Corresponding Author:phamamelie@gmail.com

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Rena Shi
Vanderbilt University Medical Center
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Andrew D. Wiese
Vanderbilt University Medical Center
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Andrew J. Spieker
Vanderbilt University Medical Center Department of Biostatistics
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Sharon E. Phillips
Vanderbilt University Medical Center Department of Biostatistics
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Margaret A. Adgent
Vanderbilt University Medical Center
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Carlos G. Grijalva
Vanderbilt University Medical Center
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Sarah S. Osmundson
Vanderbilt University Medical Center
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Abstract

Recent trends regarding GDM medication use have not been well described in prior literature. We identified pregnant patients enrolled in Tennessee Medicaid with a GDM diagnosis who a delivered in 2007 to 2019. We studied initial GDM medication use by delivery year (overall and by medication type). Over twenty percent of patients filled at least one prescription for GDM medication in the study period, with a significantly increasing prescribing trend over time. Starting in 2016, metformin replaced glyburide as the most common medication prescribed, which corresponds temporally with the emergence of evidence on the safety and effectiveness of different oral hypoglycemic medications and related changes in ACOG practice recommendations. These findings highlight how practice patterns have potential to shift quickly in response to evolving data.
02 May 2023Submitted to BJOG: An International Journal of Obstetrics and Gynaecology
02 May 2023Submission Checks Completed
02 May 2023Assigned to Editor
02 May 2023Review(s) Completed, Editorial Evaluation Pending
26 May 2023Reviewer(s) Assigned
25 Jun 2023Editorial Decision: Revise Minor
16 Jul 20231st Revision Received
16 Jul 2023Submission Checks Completed
16 Jul 2023Assigned to Editor
16 Jul 2023Review(s) Completed, Editorial Evaluation Pending
15 Aug 2023Editorial Decision: Accept