loading page

Maternal diet during pregnancy is not linked to childhood wheezing or atopic eczema
  • +2
  • Elina Sivula,
  • Heidi Puharinen,
  • Sari Hantunen,
  • Leea Keski-Nisula,
  • Katri Backman
Elina Sivula
Ita-Suomen yliopisto Laaketieteen laitos

Corresponding Author:sivula.elina@gmail.com

Author Profile
Heidi Puharinen
Ita-Suomen yliopisto Laaketieteen laitos
Author Profile
Sari Hantunen
Ita-Suomen yliopisto Kansanterveystieteen ja kliinisen ravitsemustieteen yksikko
Author Profile
Leea Keski-Nisula
Kuopion yliopistollinen sairaala
Author Profile
Katri Backman
Kuopion yliopistollinen sairaala
Author Profile

Abstract

Background: Several recent studies have investigated the association between maternal diet during pregnancy and asthma in children. However, whether a specific dietary pattern during pregnancy protects children from asthma remains unclear. This study investigated the association between a healthy diet, dietary inflammation potential during pregnancy, and the risk for wheezing and atopic eczema in children. Methods: This study included 1330 mother-child pairs who attended the Kuopio Birth Cohort (KuBiCo) study and had dietary information during the last trimester and information on children’s health in the first year of life. The Alternative Healthy Eating Index for Pregnancy (AHEI-P) and Dietary Inflammatory Index (DII) indicate a healthy diet and dietary inflammation potential during pregnancy. The AHEI-P and DII were compared with reported wheezing and doctor-diagnosed atopic eczema in children during the first year of life. Results: Neither the AHEI-P nor the DII was associated with wheezing or atopic eczema in children when analyzed by continuous variables or tertiles. The odds ratio for AHEI-P and wheezing was 0.99 (0.98–1.01); for AHEI-P and atopic eczema was 1.01 (0.99–1.02); for DII and wheezing was 1.02 (0.95–1.09), and for DII and atopic eczema was 0.97 (0.91–1.04). Conclusion: In this cohort study, a maternal healthy or anti-inflammatory diet during pregnancy was not associated with wheezing or atopic eczema in the first year of life. Interventions in the overall dietary pattern during pregnancy might not effectively prevent atopic diseases in children.
03 Apr 2023Submitted to Pediatric Allergy and Immunology
03 Apr 2023Submission Checks Completed
03 Apr 2023Assigned to Editor
03 Apr 2023Review(s) Completed, Editorial Evaluation Pending
11 Apr 2023Reviewer(s) Assigned
22 Jun 2023Editorial Decision: Revise Major
19 Sep 20231st Revision Received
19 Sep 2023Submission Checks Completed
19 Sep 2023Assigned to Editor
19 Sep 2023Review(s) Completed, Editorial Evaluation Pending
19 Sep 2023Reviewer(s) Assigned
12 Feb 20242nd Revision Received