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A Retrospective Review on the Histopathological Pattern of Childhood Malignant Solid Tumors in Ethiopia.
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  • Benjamin Watkins,
  • Rahell Hailu Ayele,
  • Yodit Getahun Yimer,
  • Yonas Bekuretsion,
  • Lulu M. Muhe,
  • Shivani A. Patel,
  • Solveig A. Cunningham,
  • Daniel Hailu
Benjamin Watkins
Emory University School of Medicine

Corresponding Author:benjamin.watkins@emory.edu

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Rahell Hailu Ayele
Addis Ababa University College of Health Sciences
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Yodit Getahun Yimer
Addis Ababa University College of Health Sciences
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Yonas Bekuretsion
Addis Ababa University College of Health Sciences
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Lulu M. Muhe
Addis Ababa University College of Health Sciences
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Shivani A. Patel
Emory University School of Public Health
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Solveig A. Cunningham
Emory University School of Public Health
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Daniel Hailu
Addis Ababa University College of Health Sciences
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Abstract

In low- and middle-income countries, malignancies remain underreported due to lack of quality data. This study outlines the histopathological pattern of pediatric solid malignancies in children aged 0-15yrs at the largest referral hospital in Ethiopia. 432 solid malignancies were evaluated. The most common malignancies were Lymphoma (21.8%), Retinoblastoma (19.4%), and Wilms tumor (13.9%). Burkitt lymphoma accounted for 2.1%, despite being the most reported pediatric malignancy in sub-Saharan Africa in published literature. Definitive diagnosis could not be made in 7% of cases, related to the lack of confirmatory testing. The study highlights the need for improvements in diagnostic capabilities in LMIC.
08 Mar 2023Submitted to Pediatric Blood & Cancer
08 Mar 2023Submission Checks Completed
08 Mar 2023Assigned to Editor
17 Mar 2023Review(s) Completed, Editorial Evaluation Pending
24 Mar 2023Reviewer(s) Assigned
10 Apr 2023Editorial Decision: Revise Minor
19 Apr 2023Submission Checks Completed
19 Apr 2023Assigned to Editor
19 Apr 20231st Revision Received
19 Apr 2023Review(s) Completed, Editorial Evaluation Pending
28 Apr 2023Editorial Decision: Accept