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Effect of Flaxseed Consumption on Central Obesity, Serum Lipids, and Adiponectin Levels in Overweight or Obese Women: A Randomized Controlled Clinical Trial
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  • hoda ahmadniay motlagh,
  • erfaneh aalipanah,
  • mohsen mazidi,
  • Shiva Faghih
hoda ahmadniay motlagh
Shiraz University of Medical Sciences

Corresponding Author:hoda.ahmadnia@gmail.com

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erfaneh aalipanah
Shiraz University of Medical Sciences
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mohsen mazidi
Chalmers University of Technology Department of Chemical and Biological Engineering
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Shiva Faghih
Shiraz University of Medical Sciences
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Abstract

Background: Flaxseed may be beneficial for the management of obesity due to its high content of alpha-linolenic acid, fiber, and lignans. Objective: We aimed to evaluate the effects of Flaxseed consumption on serum lipids, adiponectin, leptin, and weight loss in overweight or obese women. Methods: This randomized controlled clinical trial involved 60 overweight or obese women. Participants were randomly allocated to two groups; a) a balanced diet plus 30 g/day milled Flaxseed and b) a balanced diet plus 30g/day milled rice (as control group), for 12 weeks. Anthropometric indices, serum lipids, leptin, and adiponectin levels were measured at baseline and at the end of intervention. Results: After 12 weeks of intervention, there were significantly higher reductions in waist circumference (WC) and waist to hip ratio (WHR) (both P<0.05) in the flaxseed group compared to the controls. Moreover, adiponectin level was significantly increased in the flaxseed group (17.15±6.1) compared to the controls (16.83±10.5), (P=0.001). However, there were no significant differences in serum lipid levels between the study groups before and after the intervention (all p>0.05). Conclusion: Flaxseed consumption may improve adiposity markers, as well as adiponectin levels Thus, flaxseed consumption could be an adjunctive therapy to attenuate central obesity. Serum lipid profile has not changed significantly after flaxseed consumption. Keywords: obesity, flaxseed, adiponectin, Leptin, blood lipids
02 May 2021Submitted to International Journal of Clinical Practice
05 May 2021Submission Checks Completed
05 May 2021Assigned to Editor
08 May 2021Reviewer(s) Assigned
15 May 2021Review(s) Completed, Editorial Evaluation Pending
16 Jun 20211st Revision Received
18 Jun 2021Submission Checks Completed
18 Jun 2021Assigned to Editor
18 Jun 2021Review(s) Completed, Editorial Evaluation Pending
25 Jun 2021Reviewer(s) Assigned
02 Jul 2021Editorial Decision: Accept