False Endometrial Thickening in Postmenopausal Patients Using
Anticoagulants or Antiplatelets Agents
Abstract
Objective There is no report that anticoagulant or antiplatelet use may
lead to abnormal endometrial sonographic findings. This retrospective
study reports our first results associated with endometrial sampling in
asymptomatic postmenopausal women using anticoagulants or antiplatelet.
Materials methods A total of 268 postmenopausal patients who applied to
our gynecology outpatient clinic for any reasons except postmenopausal
bleeding were included in the study. Patients were divided into three
groups according to using drug status: first healty control group (HCG),
second anticoagulants agents group (ACG), and third antiplatelet agents
group (APG). The effects of anticoagulant and antiplatelet agents on
endometrial thickness were compared with histopathological findings.
Results The mean endometrial thickness was significantly greater in
group ACG (5.2 mm) and APG (4.1 m) than in group HCG (3.3 mm). No
significant differences were found in the mean endometrial thickness
between groups HCG and APG. However, it is noteworthy that the average
endomeric thickness in the ACG group is more than the other two groups
and this is statistically significant (p < 0.05). Conclusion
If the thickness of the endometrium was > 4 mm. endometrial
sampling may be recommended in in asymptomatic postmenopausal women
using anticoagulants or antiplatelet agents. Key words: Anticoagulants,
antiplatelets, biopsy, endometrial thickness, menopause, ultrasonography