loading page

Lymphangioma of the fetal neck within the PIK3CA-Related-Overgrowth Spectrum (PROS): A case report.
  • +6
  • Jann Lennard Scharf,
  • Michael Gembicki,
  • Christoph Dracopoulos,
  • Yorck Hellenbroich,
  • Anne Offermann,
  • Lars Tharun,
  • Guido Stichtenoth,
  • Kianusch Tafazzoli-Lari,
  • Jan Weichert
Jann Lennard Scharf
Universitätsklinikum Schleswig-Holstein - Campus Lübeck

Corresponding Author:jannlennard.scharf@uksh.de

Author Profile
Michael Gembicki
Universitätsklinikum Schleswig-Holstein - Campus Lübeck
Author Profile
Christoph Dracopoulos
Universitätsklinikum Schleswig-Holstein - Campus Lübeck
Author Profile
Yorck Hellenbroich
Universitätsklinikum Schleswig-Holstein - Campus Lübeck
Author Profile
Anne Offermann
Universitätsklinikum Schleswig-Holstein - Campus Lübeck
Author Profile
Lars Tharun
Universitätsklinikum Schleswig-Holstein - Campus Lübeck
Author Profile
Guido Stichtenoth
Universitätsklinikum Schleswig-Holstein - Campus Lübeck
Author Profile
Kianusch Tafazzoli-Lari
Universitätsklinikum Schleswig-Holstein - Campus Lübeck
Author Profile
Jan Weichert
Universitätsklinikum Schleswig-Holstein - Campus Lübeck
Author Profile

Abstract

Neck tumors are rare fetal conditions. They can receive their growth stimuli by activating missense mutations characterizing disorders with benign overgrowth, collectively known as PIK3CA-Related-Overgrowth-Spectrum. This results in segmental overgrowth with phenotypic variation, genetic heterogeneity or tissue specific distribution. Thus, clinical and molecular diagnosis as well as treatment remains challenging.
06 Mar 2021Submitted to Clinical Case Reports
08 Mar 2021Submission Checks Completed
08 Mar 2021Assigned to Editor
13 Mar 2021Reviewer(s) Assigned
09 May 2021Review(s) Completed, Editorial Evaluation Pending
16 May 2021Editorial Decision: Revise Minor
26 May 20211st Revision Received
31 May 2021Submission Checks Completed
31 May 2021Assigned to Editor
31 May 2021Review(s) Completed, Editorial Evaluation Pending
12 Jun 2021Editorial Decision: Accept