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Silent brain infarction after minimally invasive cardiac surgery with retrograde perfusion
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  • Shuhei Nishijima,
  • Yoshitsugu Nakamura,
  • Daiki Yoshiyama,
  • Yuto Yasumoto,
  • Miho Kuroda,
  • Taisuke Nakayama,
  • Ryo Tsuruta,
  • Yujiro Ito,
  • Fumiaki Shikata,
  • Tetuji Takeda,
  • Nobuyuki Kato
Shuhei Nishijima
Chibanishi General Hospital

Corresponding Author:shuu.nishijima@gmail.com

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Yoshitsugu Nakamura
Chibanishi General Hospital
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Daiki Yoshiyama
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Yuto Yasumoto
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Miho Kuroda
Chibanishi General Hospital
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Taisuke Nakayama
Chibanishi General Hospital
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Ryo Tsuruta
Chibanishi General Hospital
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Yujiro Ito
Chibanishi General Hospital
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Fumiaki Shikata
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Tetuji Takeda
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Nobuyuki Kato
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Abstract

Background and aim: The incidence of symptomatic cerebral infarction after minimally invasive cardiac surgery (MICS) with retrograde perfusion has been increasing. However, there is no report about silent brain infarction (SBI) after MICS with retrograde perfusion. Because SBI may cause delirium and decline of cognitive function, this condition is important clinically. Thus, the current study aimed to investigate the occurrence of SBI after MICS via magnetic resonance imaging (MRI). Methods: Between July 2014 and July 2018, 174 patients underwent MICS with retrograde perfusion and postoperative MRI in this study. Univariate and multivariate analyses were performed to examine the occurrence of SBI and to identify its risk factors. Results: Of 174 patients, 26 (14.9%) presented with SBI. The univariate analysis revealed that age and aortic valve stenosis (AS) are the risk factors of SBI. Meanwhile, multivariate analysis revealed AS as the only risk factor of SBI. Conclusions: At our institution, the incidence of SBI after MICS with retrograde perfusion was acceptable.
17 May 2020Submitted to Journal of Cardiac Surgery
18 May 2020Submission Checks Completed
18 May 2020Assigned to Editor
18 May 2020Reviewer(s) Assigned
25 May 2020Review(s) Completed, Editorial Evaluation Pending
25 May 2020Editorial Decision: Revise Major
22 Jun 20201st Revision Received
24 Jun 2020Submission Checks Completed
24 Jun 2020Assigned to Editor
24 Jun 2020Reviewer(s) Assigned
05 Jul 2020Review(s) Completed, Editorial Evaluation Pending
05 Jul 2020Editorial Decision: Accept
Aug 2020Published in Journal of Cardiac Surgery volume 35 issue 8 on pages 1927-1932. 10.1111/jocs.14866