Safety Profile of Hydroxychloroquine Sulfate vs Acetaminophen vs
Ibuprofen in Adults: A Literature Review
Abstract
Amid the 2020 Coronavirus pandemic, hydroxychloroquine sulfate (brand
name Plaquenil or abbreviated HCQ) is being explored as a potential
treatment for those affected with Covid-19 disease. Based on a limited
in-vitro and anecdotal clinical data, the U.S. Food and Drug
Administration (FDA) approved emergency use of hydroxychloroquine
sulfate as an off- label medication for hospitalized COVID-19 patients
weighing 50kg or more.1 Research Questions: 1. What is the safety
profile of hydroxychloroquine sulfate compared to common outpatient
medications such as acetaminophen and ibuprofen in terms of major and
minor adverse effects? 2. Could hydroxychloroquine sulfate be used as an
outpatient medication to treat COVID- 19?