On the 22^nd of May 2021, although no alarming precursory unrest had been reported, Nyiragongo volcano erupted and lava flows threatened about 1 million of inhabitants living in the cities of Goma (Democratic Republic of Congo) and Giseny (Rwanda). After January 1977 and January 2002, it was the beginning of the third historically known flank eruption of Nyiragongo volcano and the first ever to be recorded by dense measurements both on the ground and from space. In the following days, seismic and geodetic data as well as fracture mapping revealed the gradual southward propagation of a shallow dike from the Nyiragongo edifice underlying below Goma airport on May 23-24, then Goma and Gisenyi city centers on May 25-26 and finally below the northern part of Lake Kivu on May 27. Southward migration of the associated seismic swarm slowed down between May 27 and June 02. Micro seismicity became more diffuse, progressively activating transverse tectonic structures previously identified in the whole Lake Kivu basin. Here we exploit ground based and remote sensing data as well as inversion and physics-based models to fully characterize the dike sized, the dynamics of dike propagation and its arrest against a structural lineament known as the Nyabihu Fault. This work highlights the shallow origin of the dike, the segmented dike propagation controlled by the interaction with pre-existing fracture networks and the incremental crater collapse associated with drainage which led to the disappearance of the world’s largest long-living lava lake on top of Nyiragongo.