Sand production is the process in which formation sand and gravel would migrate into the wellbore by the flow of reservoir fluids. This is a problem that endangers the safety of hydrate exploitation. The aim of this study is to understand sand production in during hydrate exploitation. A novel experimental apparatus was constructed to examine sand production in the hydrate-bearing sediments by applying the depressurization method. The maximum pressure of apparatus is 30 MPa, the temperature could be controlled from -253.15 to 313.15 K. The pore pressure, crustal stress, production pressure, gas flow rate, water production volume and subsidence rates could be measured. The vertical wellbore comprised liner 1 (ø32 mm × 135 mm, 3 mm holes, arrangement: 36°, holes row gap: 10 mm) and liner 3 (ø24 mm × 135 mm, 2.5 mm holes, arrangement: 36°, hole row gap: 10 mm) with a sand screen. Besides gas in from top, the sediment chamber (ø158 mm × 120 mm) had a middle mesh screen that allowed gas and water enter or vacuumize the chamber circumferentially around the sediments (ø158 mm × 100 mm). Sand production situation was recorded by HD camera through the visual window on the gas-solid-liquid separator. Hydrate production was divided into three periods: water, gas with water drops, and gas. We found fine sand production in the first period and sand grains production in the second. The sand production behaviours through the different gas production rates in two production method - depletion gas production curve and stable gas production curve were discussed. The grain sizes of sand production were increasing in the production period with hydrate saturation decreasing. The temperature related characteristics of the hydrate layers differed during different stages of hydrate production. The unique sputtering occurring owing to the decomposition of the hydrate might have provided the driving force for sand migration, and water gas bubbles or gaseous water drops from the decomposed hydrate might have enhanced sand carrying capacity. The subsidence of hydrate-bearing sediments was influenced by sand production, whereas the maintenance of crustal stress possibly influenced the rate and magnitude of subsidence. The stimulation at late production in low hydrate saturation might conduct the subsidence and sand production increased dramatically.